Pharmaceutical salts.
نویسندگان
چکیده
Keyphrases D Pharmaceutical salts-general pharmacy, physicochemical properties, bioavailability, pharmaceutical properties, toxicology, review J:J Salts, pharmaceutical-general pharmacy, physicochemical properties, bioavailability, pharmaceutical properties, toxicology, review J:J Physicochemical properties-dissolution, solubility, stability, and organoleptic properties of pharmaceutical salts, review [] Bioavailability-formulation effects, absorption alteration and pharmacokinetics of pharmaceutical salts, review D Toxicology-pharmaceutical salts, review
منابع مشابه
Conformation of 1,4-dineopentyl-2,5-cis-diphenylpiperazine and its diammonium salts: remarkable change in conformation depending upon the counter anion.
The free base of 1,4-dineopentyl-2,5-diphenylpiperazine takes a chair conformation in CDCl3, while the conformation of its diammonium salts changes depending upon the counter anion.
متن کاملConformational difference between mono- and diprotonated cis-2,5-diphenylpiperazinium salts in the solid state.
Monohydrochlorides of cis-2,5-diphenylpiperazine assume a chair conformation, while the corresponding dihydrochlorides assume a boat form regardless of the substituent(s) at the nitrogen atom.
متن کاملReaction of 1-alkylthioisoquinolinium salts with active methylene compounds.
2-Alkyl-1-alkylthioisoquinolinium salts were readily prepared from 2-alkyl-1(2H)-isoquinolones via 2-alkyl1(2H)-thioisoquinolones in two steps. Under mild conditions, the reaction of 2-alkyl-1-alkylthioisoquinolinium salts with active methylene compounds in the presence of sodium hydride afforded 2-alkyl-1-(substituted methylene)iso-quinolines in good yields. Pyrrolo[2,1-a]isoquinolines were sy...
متن کاملN-heterocyclic carbene ligands in copper-catalyzed addition of diethylzinc to N-sulfonylimines.
N-Heterocyclic carbenes (NHCs) were generated in-situ from imidazolium and imidazolinium salts by deprotonation of C-2 hydrogen and were used as ligands in the copper-catalyzed addition of diethylzinc to N-sulfonylimines. The copper-NHC complexes were shown to possess an efficient ligand acceleration effect (LAE).
متن کاملRh-N-heterocyclic carbene (NHC) complex-catalyzed addition of phenylboronic acid to N-sulfonyl and N-phosphinoyl aldimines.
Rh-N-heterocyclic carbene (NHC) complexes were generated in situ from imidazolium salts, [RhCl(cod)](2) and t-BuOK in dioxane. In the presence of a catalytic amount of Rh-NHC complexes, the addition reaction of phenylboronic acid to N-sulfonylarylimines and N-phosphinyolarylimines gave the corresponding amines in high yields.
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ورودعنوان ژورنال:
- Journal of pharmaceutical sciences
دوره 66 1 شماره
صفحات -
تاریخ انتشار 1977